Dengue Fever: In-Hospital Management of Critically ill Adult Patients

  • kiran Fatima Islamic International Medical College, Rawalpindi
  • Aamir Shahzad National University of Medical Sciences, Rawalpindi
Keywords: Dengue, Dengue Hemorrhagic Fever, Dengue Shock Syndrome.

Abstract

Dengue is rapidly becoming a major public health problem with significant mortality and morbidity. Management especially in first two days needs careful attention. We present a review of current literature on the management critically ill adult patients of dengue in hospital settings. Early diagnosis and close monitoring of response to treatment are necessary to prevent worse outcomes.

References

Rasheed SB, Butlin RK, Boots M. A review of dengue as an emerging disease in Pakistan. Public Health 2013; 127: 11-7. 2. Wichmann O, Hongsiriwon S, Bowonwatanuwong C, Chotivanich K, Sukthana Y, Pukrittayakamee S. Risk factors and clinical features associated with severe dengue infection in adults and children during the 2001 epidemic in

Chonburi, Thailand. Trop Med Int Health. 2004; 9: 1022-9.

Wills BA, Oragui EE, Stephens AC, Daramola OA, Dung NM, Loan HT, et al. Coagulation abnormalities in dengue hemorrhagic fever: serial investigations in 167 Vietnamese children with dengue shock syndrome. Clin Infect Dis. 2002;

: 277-85.

Kalayanarooj S, Nimmannitya S. Guidelines for DHF case management for workshop on case management of Dengue Hemorrhagic fever. WHO collaborating center for case management of Dengue/DHF/DSS. June 10-15, 2002.

Dung NM, Day NP, Tam DT, Loan HT, Chau HT, Minh LN, et al. Fluid replacement in dengue shock syndrome: a randomized double-blind comparison of four intravenous- fluid regiments. Clin infect Dis. 1999; 29: 787-94.

Nhan NT, Phuong CX, Kneen R, Wills B, Van My N, Phuong NT, et al. Acute management of dengue shock syndrome: a randomized double-blind comparison of 4 intravenous fluid regimens in the first hour. Clin Infect Dis. 2001; 32: 204-13.

Wills BA, Dung NM, Loan HT, Tam DT, Thuy TT, Minh LT, et al. Comparison of three fluid solutions for resuscitation in dengue shock syndrome. N Engl J Med. 2005; 353: 877-89.

Dengue hemorrhagic fever: diagnosis, treatment, prevention and control. 2nd ed. Geneva: World health organization: 1997. Available at http//w3.who.

Wills BA, Oragui EE, Stephens AC, Daramola OA, Dung NM, Loan HT, et al. Coagulation abnormalities in dengue hemorrhagic fever: serial investigations in 167 Vietnamese children with dengue shock syndrome. Clin Infect Dis. 2002; 35: 277-8.

Wills B, Van Ngoc T, Van NT, Thuy TT, Thuy TT, Dung NM, et al. Hemostatic changes in Vietnamese children with mild dengue correlate with the severity of vascular leakage rather than bleeding. Am J Trop Med Hyg. 2009; 81: 638-4.

Mairuhu AT, Mac Gillavry MR, Setiati TE, Soemantri A, Ten Cate H, Brandjes DP, et al. Is clinical outcome of denguevirus infections influenced by coagulation and fibrinolysis? A critical review of the evidence. Lancet Infect Dis. 2003; 3: 33-41.

Subcommittee of technical experts on clinical management of DF/DGF. Guidelines on clinical management of dengue/dengue hemorrhagic fever. Sri Lanka. 2005. Available at http//www.epid.gov.il.pdf/guidelines.

Lum LC, Goh AY, Chan PW, El-Amin AL, Lam S. Risk factors for hemorrhage in severe dengue infections.J Paediatr. 2002; 140: 629-31.

Chairulfatah A, Setiabudi D, Agoes R, Colebunders R. Thrombocytopenia and platelet transfusions in dengue hemorrhagic fever and dengue shock syndrome. Dengue Bulletin. 2003; 27: 138-43.

Lum LC, Abdel-Latif ME, Goh AY, Chan PW, Lam SK. Preventive transfusion in DSS-is it necessary? Pediatr. 2003; 143: 682-4.

Chiu YC, Wu KL, Kuo CH, Hu TH, Chou YP, Chuah SK, et al. Endoscopic findings and management of dengue patients with upper gastrointestinal bleeding Am J Top Med Hyg. 2005; 73: 41-4.

Chuansumrit A, Wangruangsatid S, Lektrakul Y, Chua MN, Capeding MR, Bech OM, et al. Dengue study group. Control of bleeding in children with DHF using recombinant activated factor VII: a randomized, doble-blind, placebo- controlled study. Blood Coagul Fibrinolysis. 2005; 16: 549- 55.

Chuansumrit A, Tangnaraiatchakir K, Lektakul Y. The use of recombinant activated factor VII for controlling life threatening bleeding in DSS. Blood Coagul Fibrinolysis. 2004; 15: 335-42.

United Kingdom Hemophilia Center Doctors Organisation (UKHCDO) Guidelines on the selection and use of therapeutic products to treat hemophilia and oter hereditary bleeding disorders. Hemophilia. 2003; 9: 1-23.

Marino PL. Principles of mechanical ventilation. 3rd ed. USA: Lippincolt Williams and Wilkins. 2007; p: 461.

Riley B. Oh's intensive Care Manual. 5thed, China: Butterworth-Heinmann; Elsevier Limited. 2003: p: 496.

Pinnock CA, Lin T, Smith T. Indications for intubations and

ventilatiolns after head injury. In Fundamentals of anesthesia. 2nd edition. Cambridge university press; 2002; P: 179.

Task force of the American college of clinical care medicine. Society of critical care medicine. Practice parameters for hemodynamic support of sepsis in adult patients in sepsis. Crit Care Med. 1999; 27: 639-60.

Graber D. Daile RH. Catheter flow rates updated. JACEP. 1977; 6: 518.

Doerfler ME, Kaufman B, Goldenberg AS. Central venous catheter placement in patients with disorders of hemostasis. Chest. 1996; 110: 185-88.

Mumtaz H, Williams V, Hauer-Jensen M, Rowe M, Henry- Tillman RS, Heaton KM, et al. Central venous catheter placement in patients with disorders of hemostasis. Am J surg. 2000; 180: 503-5.

McGee DC, Gould MK. Current concepts: preventing complications of central venous catheters. New Eng J Med.

; 348: 1123-33.

Taylor RW, Palagiri AV. Central venous catheterization. Crit Care Med. 2007; 35: 1390-6.

Frezza EE, Mezghebe H. Indications and complications of arterial catheter use in surgical or medical intensive care units: analysis of 4932 patients. Am Surg. 198; 64: 127-31.

Soni A, Chugh K, Sachdev A, Gupta D. Management of dengue fever in ICU. Indian J Pediatr. 2001; 68: 1051-5.

Wang WK, Chao DY, Kao CL, Wu HC, Liu YC, Li CM, et al. High levels of plasma dengue viral load during defervescence in patients with dengue hemorrhagic fever: Implications for pathogenesis. Virology. 2003; 305: 330-8.

Waduge R, Malavige GN, Pradeepan M, Wijeyaratne CN, Fernando S, Seneviratne SL. Dengue infections during pregnancy: a case series from Sri Lanka ad review of the literature, J Clin Virol. 2006; 37: 27-33.

Ismail NA, Kampan N, Mehdy ZA. Dengue in pregnancy. South Asia J Trop Med Public health. 2006; 37: 681-3.

De Roeck D, Deen J, Clemens JD. Policymakers views on dengue fever/dengue hemorrhagic fever and the need for dengue vaccination in four south Asian countries. Vaccine. 2003; 22: 121-9.

Carles G, Peiffer H, Talarmin A. Effects of dengue fever during pregnancy in French Guiana. Clin Infect Dis. 1999; 28: 637-40.

Verdeal JC, Costa Filho R, Vanzillotta C, Macedo GL, Bozza FA, Toscano L, et al. Rev Bras Ter Intensiva. 2011; 23: 125-33.

Published
2021-04-02
Section
Review Article