COVID-19 and Impact of Nutrition

  • Sara Mumtaz National University of Medical Sciences, Rawalpindi
  • Rida Fatima Saeed National University of Medical Sciences, Rawalpindi
  • Asma Saleem Qazi National University of Medical Sciences, Rawalpindi
Keywords: COVID-19, Dietary Pattern, Nutrition, Vitamins

Abstract

Coronavirus disease (COVID-19) is an infectious disease that is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has affected the entire world. The clinical course of infection varies from asymptomatic to mild symptoms to life threatening conditions in affected individuals. An unbalanced immune response is responsible for many complications and even death in severe cases. Poor nutritional status is a major risk factor for infection as it makes the patient immunocompromised. A good dietary pattern boost immune system in combating infections. In this review, the role of various dietary patterns, individual vitamins and trace elements will be considered. The link between diet and COVID-19 has yet to be established. However, findings from previous studies on respiratory tract infections have shown that diet plays an important role in the management and prevention of infections.

References

WuF,ZhaoS,YuB,ChenYM,WangW,SongZG,etal.Anew coronavirus associated with human respiratory disease in China. Nature. 2020; 579: 265–9.

Xu Z, Shi L, Wang Y, Zhang J, Huang L, Zhang C, et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med. 2020; 8: 420-22.

Rothan AH, Byrareddy NS. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun. 2020; 109: 102433.

Wang HJ, Du SH, Yue X, Chen CX. Review and Prospect of Pathological Features of Corona Virus Disease. Fa Yi Xue Za Zhi. 2020; 36: 16-20.

Feng He, Yu Deng, Weina Li. Coronavirus disease 2019: What we know? J Med Virol. 2020; 92: 719-25.

Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges. Int J Antimicrob Agents. 2020; 55: 105924.

Zaim S, Chong JH, Sankaranarayanan V, Harky A. COVID-19 and Multiorgan Response. Curr Probl Cardiol. 2020; 45: 100618.

Gheblawi M, Wang K, Viveiros A, Nguyen Q, Zhong JC, Turner AJ, et al. Angiotensin converting enzyme 2: SARS- CoV-2 receptor and regulator of the renin-angiotensin system. Circ Res. 2020; 126: 1456–74.

Walls AC, Park YJ, Tortorici MA, Wall A, McGuire AT, Veesler D. Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein. Cell. 2020; 181: 281-92.

Tay MZ, Poh CM, Rénia L, MacAry PA, Ng LFP. The trinity of COVID-19: immunity, inflammation and intervention. Nat Rev Immunol. 2020; 20: 363-74.

Tobaiqy M, Qashqary M, Al-Dahery S , Mujallad A, Hershan AA, Kamal MA, et al. Therapeutic management of patients with COVID-19: a systematic review. Infection Prevention in Practice. 2020; 2: 100061.

Chu KH, Tsang WK, Tang CS, Lam MF, Lai FM, To KF, et al. Acute renal impairment in coronavirus-associated severe acute respiratory syndrome. Kidney Int. 2005; 67: 698-705.

Cordain L, Eaton SB, Sebastian A, Mann N, Lindeberg S, Watkins BA. Origins and evolution of the Western diet: health implications for the 21st century. Am. J. Clin. Nutr. 2005; 81: 254-341.

Dietz W, Santos-Burgoa C. Obesity and its implications for COVID-19 mortality. Obesity. 2020; 28: 1005.

LiX,XuS,YuM,WangK,TaoY, ZhouY,etal.Riskfactorsfor severity and mortality in adult COVID-19 inpatients in Wuhan.J.AllergyClinImmunol. 2020;146:110-18

Butlera MJ, Barrientosa RM. The impact of nutrition on COVID-19 susceptibility and long-term consequences. Brain Behav Immun. 2020; 87: 53–4.

Mazzocchi A, Leone L, Agostoni C, Pali-Schöll I. The Secrets of the Mediterranean Diet. Does [Only] Olive Oil Matter? Nutrients. 2019; 11: 2941.

Casas R, Sacanella E, Estruch R. The immune protective effect of the Mediterranean diet against chronic low-grade inflammatory diseases. Endocr Metab Immune Disord Drug Targets. 2014; 14: 245-54.

Martinez-Gonzalez MA, Bes-Rastrollo M. Dietary patterns, Mediterranean diet, and cardiovascular disease. Curr Opin Lipidol. 2014; 25: 20–6.

Pinto A, Bonucci A, Maggi E, Corsi M, Businaro R. Anti- Oxidant and Anti-Inflammatory Activity of Ketogenic Diet: New Perspectives for Neuroprotection in Alzheimer's Disease. Antioxidants (Basel). 2018; 7: 63.

Augustin K, Khabbush A, Williams S, Eaton S, Orford M, Cross JH, et al. Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders. Lancet Neurol. 2018; 17: 84–93.

JiaX,WangZ,ZhangB,SuC,DuW,ZhangJ,etal.Food Sources and Potential Determinants of Dietary Vitamin C Intake in Chinese Adults: A Cross-Sectional Study. Nutrients. 2018; 10: 320.

Martin-Calvo N, Martinez-Gonzalez MA. Vitamin C Intake is Inversely Associated with Cardiovascular Mortality in a Cohort of Spanish Graduates: The SUN Project. Nutrients. 2017; 9: 954.

Carr AC, Maggini S. Vitamin C and Immune Function. Nutrients. 2017; 9: 1211.

Carr AC. A new clinical trial to test high-dose vitamin C in patients with COVID-19. Crit Care. 2020; 24: 133.

Lee GY, Han SN. The role of vitamin E in immunity. Nutrients. 2018; 10: 1614.

Lips P, Hosking D, Lippuner K, Norquist JM, Wehren L,

Maalouf G. The prevalence of vitamin D inadequacy

amongst women with osteoporosis: An international 710.

epidemiological investigation. J Intern Med. 2006; 260:

–54.

Nair R, Maseeh A. Vitamin D: The “sunshine” vitamin. J

Pharmacol Pharmacother. 2012; 3: 118–26.

Agrawal DK, Yin K. Vitamin D and inflammatory diseases. J

Inflamm Res. 2014; 7: 69–87.

Biesalsk HK. Vitamin D deficiency and co-morbidities in

COVID-19 patients – A fatal relationship?” NFS Journal.

; 20: 10–21.

Grant WB, Lahore H, McDonnell SL, Baggerly CA, French CB,

Aliano JL, et al. Evidence that vitamin d supplementation could reduce risk of influenza and COVID-19 infections and deaths. Nutrients. 2020; 12: 988.

JiaX,WangZ,ZhangB,SuC,DuW,ZhangJ,etal.Food Sources and Potential Determinants of Dietary Vitamin C Intake in Chinese Adults: A Cross-Sectional Study. Nutrients. 2018; 10: 320.

Martin-Calvo N, Martinez-Gonzalez MA. Vitamin C Intake is Inversely Associated with Cardiovascular Mortality in a Cohort of Spanish Graduates: The SUN Project. Nutrients. 2017; 9: 954.

Carr AC, Maggini S. Vitamin C and Immune Function. Nutrients. 2017; 9: 1211.

Carr AC. A new clinical trial to test high-dose vitamin C in patients with COVID-19. Crit Care. 2020; 24: 133.

Lee GY, Han SN. The role of vitamin E in immunity. Nutrients. 2018; 10: 1614.

Read SA, Obeid S, Ahlenstiel C, Ahlenstiel G The role of zinc in antiviral immunity. Advances in Nutrition. 2019; 10: 696-710.

Prasad AS. Discovery of human zinc deficiency: its impact on human health and disease. Advances in nutrition. 2013; 4: 176-90.

Zheng YY, Ma YT, Zhang JY, Xie X. COVID-19 and the cardiovascular system. Nature Rev Cardiol. 2020; 17: 259–60.

Borkow G, Gadi J. Copper, an ancient remedy returning to fight microbial, fungal and viral infections. Current Chemical Biology. 2009; 3: 272-278.

Jayawardena R, Sooriyaarachchi P, Chourdakis M, Jeewandara C, Ranasinghe P. Enhancing immunity in viral infections, with special emphasis on COVID-19: A review. Diabetes Metab Syndr. 2020; 14: 367-82.

Published
2020-12-23